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Targeting Polyamine Oxidase to Prevent Excitotoxicity-Induced Retinal Neurodegeneration

Dysfunction of retinal neurons is a major cause of vision impairment in blinding diseases that affect children and adults worldwide. Cellular damage resulting from polyamine catabolism has been demonstrated to be a major player in many neurodegenerative conditions. We have previously shown that inhi...

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Detalles Bibliográficos
Autores principales: Pichavaram, Prahalathan, Palani, Chithra Devi, Patel, Chintan, Xu, Zhimin, Shosha, Esraa, Fouda, Abdelrahman Y., Caldwell, Ruth B., Narayanan, Subhadra Priya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335392/
https://www.ncbi.nlm.nih.gov/pubmed/30686964
http://dx.doi.org/10.3389/fnins.2018.00956