Cargando…
Targeting Polyamine Oxidase to Prevent Excitotoxicity-Induced Retinal Neurodegeneration
Dysfunction of retinal neurons is a major cause of vision impairment in blinding diseases that affect children and adults worldwide. Cellular damage resulting from polyamine catabolism has been demonstrated to be a major player in many neurodegenerative conditions. We have previously shown that inhi...
Autores principales: | Pichavaram, Prahalathan, Palani, Chithra Devi, Patel, Chintan, Xu, Zhimin, Shosha, Esraa, Fouda, Abdelrahman Y., Caldwell, Ruth B., Narayanan, Subhadra Priya |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335392/ https://www.ncbi.nlm.nih.gov/pubmed/30686964 http://dx.doi.org/10.3389/fnins.2018.00956 |
Ejemplares similares
-
Pharmacological Inhibition of Spermine Oxidase Reduces Neurodegeneration and Improves Retinal Function in Diabetic Mice
por: Liu, Fang, et al.
Publicado: (2020) -
Pharmacological Inhibition of Spermine Oxidase Suppresses Excitotoxicity Induced Neuroinflammation in Mouse Retina
por: Alfarhan, Moaddey, et al.
Publicado: (2022) -
Retinal Neuroprotection From Optic Nerve Trauma by Deletion of Arginase 2
por: Xu, Zhimin, et al.
Publicado: (2018) -
Is the Arginase Pathway a Novel Therapeutic Avenue for Diabetic Retinopathy?
por: Shosha, Esraa, et al.
Publicado: (2020) -
Deletion of arginase 2 attenuates neuroinflammation in an experimental model of optic neuritis
por: Candadai, Amritha A., et al.
Publicado: (2021)