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Late relapse in acute myeloid leukemia (AML): clonal evolution or therapy-related leukemia?

Late relapse, defined as relapse arising after at least 5 years of remission, is rare and occurs in 1–3% of patients with acute myeloid leukemia (AML). The underlying mechanisms of late relapse remain poorly understood. We identified patients with AML who achieved remission with standard induction c...

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Detalles Bibliográficos
Autores principales: Yilmaz, Musa, Wang, Feng, Loghavi, Sanam, Bueso-Ramos, Carlos, Gumbs, Curtis, Little, Latasha, Song, Xingzhi, Zhang, Jianhua, Kadia, Tapan, Borthakur, Gautam, Jabbour, Elias, Pemmaraju, Naveen, Short, Nicholas, Garcia-Manero, Guillermo, Estrov, Zeev, Kantarjian, Hagop, Futreal, Andrew, Takahashi, Koichi, Ravandi, Farhad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335405/
https://www.ncbi.nlm.nih.gov/pubmed/30651532
http://dx.doi.org/10.1038/s41408-019-0170-3