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Exosomes harbor B cell targets in pancreatic adenocarcinoma and exert decoy function against complement-mediated cytotoxicity

Although B cell response is frequently found in cancer, there is little evidence that it alters tumor development or progression. The process through which tumor-associated antigens trigger humoral response is not well delineated. We investigate the repertoire of antigens associated with humoral imm...

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Detalles Bibliográficos
Autores principales: Capello, Michela, Vykoukal, Jody V., Katayama, Hiroyuki, Bantis, Leonidas E., Wang, Hong, Kundnani, Deepali L., Aguilar-Bonavides, Clemente, Aguilar, Mitzi, Tripathi, Satyendra C., Dhillon, Dilsher S., Momin, Amin A., Peters, Haley, Katz, Matthew H., Alvarez, Hector, Bernard, Vincent, Ferri-Borgogno, Sammy, Brand, Randall, Adler, Douglas G., Firpo, Matthew A., Mulvihill, Sean J., Molldrem, Jeffrey J., Feng, Ziding, Taguchi, Ayumu, Maitra, Anirban, Hanash, Samir M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335434/
https://www.ncbi.nlm.nih.gov/pubmed/30651550
http://dx.doi.org/10.1038/s41467-018-08109-6