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Visualizing the Contribution of Keratin-14(+) Limbal Epithelial Precursors in Corneal Wound Healing

It is thought that corneal epithelial injuries resolve by leading-edge cells “sliding” or “rolling” into the wound bed. Here, we challenge this notion and show by real-time imaging that corneal wounds initially heal by “basal cell migration.” The K14CreER(T2)-Confetti multi-colored reporter mouse wa...

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Detalles Bibliográficos
Autores principales: Park, Mijeong, Richardson, Alexander, Pandzic, Elvis, Lobo, Erwin P., Whan, Renee, Watson, Stephanie L., Lyons, J. Guy, Wakefield, Denis, Di Girolamo, Nick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335450/
https://www.ncbi.nlm.nih.gov/pubmed/30554917
http://dx.doi.org/10.1016/j.stemcr.2018.11.014