Origin of the Mobile Di-Hydro-Pteroate Synthase Gene Determining Sulfonamide Resistance in Clinical Isolates

Sulfonamides are synthetic chemotherapeutic agents that work as competitive inhibitors of the di-hydro-pteroate synthase (DHPS) enzyme, encoded by the folP gene. Resistance to sulfonamides is widespread in the clinical setting and predominantly mediated by plasmid- and integron-borne sul1-3 genes en...

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Detalles Bibliográficos
Autores principales: Sánchez-Osuna, Miquel, Cortés, Pilar, Barbé, Jordi, Erill, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335563/
https://www.ncbi.nlm.nih.gov/pubmed/30687297
http://dx.doi.org/10.3389/fmicb.2018.03332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335563/
https://www.ncbi.nlm.nih.gov/pubmed/30687297
http://dx.doi.org/10.3389/fmicb.2018.03332

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