A miRNA-Mediated Approach to Dissect the Complexity of Tumor-Initiating Cell Function and Identify miRNA-Targeting Drugs

Tumor-initiating cells (TICs) contribute to drug resistance and tumor recurrence in cancers, thus experimental approaches to dissect the complexity of TICs are required to design successful TIC therapeutic strategies. Here, we show that miRNA-3′ UTR sensor vectors can be used as a pathway-based meth...

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Detalles Bibliográficos
Autores principales: Belur Nagaraj, Anil, Joseph, Peronne, Ponting, Erin, Fedorov, Yuriy, Singh, Salendra, Cole, Alex, Lee, Woncheol, Yoon, Euisik, Baccarini, Alessia, Scacheri, Peter, Buckanovich, Ronald, Adams, Drew J., Drapkin, Ronny, Brown, Brian D., DiFeo, Analisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335585/
https://www.ncbi.nlm.nih.gov/pubmed/30629937
http://dx.doi.org/10.1016/j.stemcr.2018.12.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335585/
https://www.ncbi.nlm.nih.gov/pubmed/30629937
http://dx.doi.org/10.1016/j.stemcr.2018.12.002

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