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A miRNA-Mediated Approach to Dissect the Complexity of Tumor-Initiating Cell Function and Identify miRNA-Targeting Drugs
Tumor-initiating cells (TICs) contribute to drug resistance and tumor recurrence in cancers, thus experimental approaches to dissect the complexity of TICs are required to design successful TIC therapeutic strategies. Here, we show that miRNA-3′ UTR sensor vectors can be used as a pathway-based meth...
Autores principales: | Belur Nagaraj, Anil, Joseph, Peronne, Ponting, Erin, Fedorov, Yuriy, Singh, Salendra, Cole, Alex, Lee, Woncheol, Yoon, Euisik, Baccarini, Alessia, Scacheri, Peter, Buckanovich, Ronald, Adams, Drew J., Drapkin, Ronny, Brown, Brian D., DiFeo, Analisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335585/ https://www.ncbi.nlm.nih.gov/pubmed/30629937 http://dx.doi.org/10.1016/j.stemcr.2018.12.002 |
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