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Serum levels of proteins involved in amyloid-β clearance are related to cognitive decline and neuroimaging changes in mild cognitive impairment

INTRODUCTION: Amyloid-β (Aβ) clearance is important for damage prevention in Alzheimer's disease. We investigated the utility of Aβ clearance proteins as biomarkers for mild cognitive impairment (MCI). METHODS: Serum apolipoprotein (apo) A-I, compliment protein C3 (C3), transthyretin, and chole...

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Detalles Bibliográficos
Autores principales: Liu, Shan, Suzuki, Hideaki, Ito, Hitomi, Korenaga, Tatsumi, Akatsu, Hiroyasu, Meno, Kohji, Uchida, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335589/
https://www.ncbi.nlm.nih.gov/pubmed/30671532
http://dx.doi.org/10.1016/j.dadm.2018.11.003