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Clathrin-Mediated Endocytosis Regulates a Balance between Opposing Signals to Maintain the Pluripotent State of Embryonic Stem Cells

Endocytosis is implicated in the maintenance of embryonic stem cell (ESC) pluripotency, although its exact role and the identity of molecular players remain poorly understood. Here, we show that the clathrin heavy chain (CLTC), involved in clathrin-mediated endocytosis (CME), is vital for maintainin...

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Detalles Bibliográficos
Autores principales: Narayana, Yadavalli V., Gadgil, Chetan, Mote, Ridim D., Rajan, Raghav, Subramanyam, Deepa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335602/
https://www.ncbi.nlm.nih.gov/pubmed/30554918
http://dx.doi.org/10.1016/j.stemcr.2018.11.018