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A divergent synthetic pathway for pyrimidine-embedded medium-sized azacycles through an N-quaternizing strategy

Medium-sized heterocycles have recently received significant attention because of their potential roles as modulators of protein–protein interactions, but their molecular diversity and synthetic availability are still inadequate to meet the demand. To address these issues, we developed a new diverge...

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Detalles Bibliográficos
Autores principales: Choi, Yoona, Kim, Heejun, Park, Seung Bum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335630/
https://www.ncbi.nlm.nih.gov/pubmed/30746098
http://dx.doi.org/10.1039/c8sc04061c