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Characterisation of the biosynthetic pathway to agnestins A and B reveals the reductive route to chrysophanol in fungi

Two new dihydroxy-xanthone metabolites, agnestins A and B, were isolated from Paecilomyces variotii along with a number of related benzophenones and xanthones including monodictyphenone. The structures were elucidated by NMR analyses and X-ray crystallography. The agnestin (agn) biosynthetic gene cl...

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Detalles Bibliográficos
Autores principales: Szwalbe, Agnieszka J., Williams, Katherine, Song, Zhongshu, de Mattos-Shipley, Kate, Vincent, Jason L., Bailey, Andrew M., Willis, Christine L., Cox, Russell J., Simpson, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335632/
https://www.ncbi.nlm.nih.gov/pubmed/30746079
http://dx.doi.org/10.1039/c8sc03778g