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SIRT6/HIF-1α axis promotes papillary thyroid cancer progression by inducing epithelial–mesenchymal transition

BACKGROUND: In our previous study, we demonstrated that Sirtuin 6 (SIRT6) is upregulated and associated with papillary thyroid cancer (PTC) progression (Qu et al. in Int J Oncol 50(5):1683–92, 2017). This study examined whether SIRT6 promotes epithelial–mesenchymal transition (EMT) of papillary thyr...

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Detalles Bibliográficos
Autores principales: Yang, Zhou, Yu, Weiping, Huang, Renhong, Ye, Min, Min, Zhijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335740/
https://www.ncbi.nlm.nih.gov/pubmed/30675128
http://dx.doi.org/10.1186/s12935-019-0730-4