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Transplantation of neural precursors generated from spinal progenitor cells reduces inflammation in spinal cord injury via NF-κB pathway inhibition

BACKGROUND: Traumatic spinal cord injury (SCI) triggers a chain of events that is accompanied by an inflammatory reaction leading to necrotic cell death at the core of the injury site, which is restricted by astrogliosis and apoptotic cell death in the surrounding areas. Activation of nuclear factor...

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Detalles Bibliográficos
Autores principales: Karova, Kristyna, Wainwright, John V., Machova-Urdzikova, Lucia, Pisal, Rishikaysh V., Schmidt, Meic, Jendelova, Pavla, Jhanwar-Uniyal, Meena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335809/
https://www.ncbi.nlm.nih.gov/pubmed/30654804
http://dx.doi.org/10.1186/s12974-019-1394-7