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Transplantation of neural precursors generated from spinal progenitor cells reduces inflammation in spinal cord injury via NF-κB pathway inhibition
BACKGROUND: Traumatic spinal cord injury (SCI) triggers a chain of events that is accompanied by an inflammatory reaction leading to necrotic cell death at the core of the injury site, which is restricted by astrogliosis and apoptotic cell death in the surrounding areas. Activation of nuclear factor...
Autores principales: | Karova, Kristyna, Wainwright, John V., Machova-Urdzikova, Lucia, Pisal, Rishikaysh V., Schmidt, Meic, Jendelova, Pavla, Jhanwar-Uniyal, Meena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335809/ https://www.ncbi.nlm.nih.gov/pubmed/30654804 http://dx.doi.org/10.1186/s12974-019-1394-7 |
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