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TLR9 polymorphism correlates with immune activation, CD4 decline and plasma IP10 levels in HIV patients
BACKGROUND: The mechanism behind HIV mediated immune activation remains debated, although the role of virus replication in this process is increasingly evident. Toll like Receptor 9 (TLR9) has been implicated in HIV mediated immune activation via sensing of viral CpG DNA. Polymorphisms in the TLR9 g...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335820/ https://www.ncbi.nlm.nih.gov/pubmed/30651082 http://dx.doi.org/10.1186/s12879-019-3697-9 |