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TLR9 polymorphism correlates with immune activation, CD4 decline and plasma IP10 levels in HIV patients

BACKGROUND: The mechanism behind HIV mediated immune activation remains debated, although the role of virus replication in this process is increasingly evident. Toll like Receptor 9 (TLR9) has been implicated in HIV mediated immune activation via sensing of viral CpG DNA. Polymorphisms in the TLR9 g...

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Detalles Bibliográficos
Autores principales:	Joshi, Anjali, Punke, Erin B., Mehmetoglu-Gurbuz, Tugba, Peralta, Diego P., Garg, Himanshu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335820/ https://www.ncbi.nlm.nih.gov/pubmed/30651082 http://dx.doi.org/10.1186/s12879-019-3697-9

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