Dalmanol biosyntheses require coupling of two separate polyketide gene clusters

Polyketide–polyketide hybrids are unique natural products with promising bioactivity, but the hybridization processes remain poorly understood. Herein, we present that the biosynthetic pathways of two immunosuppressants, dalmanol A and acetodalmanol A, result from an unspecific monooxygenase trigger...

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Detalles Bibliográficos
Autores principales: Zhou, Zhen Zhen, Zhu, Hong Jie, Lin, Li Ping, Zhang, Xuan, Ge, Hui Ming, Jiao, Rui Hua, Tan, Ren Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335865/
https://www.ncbi.nlm.nih.gov/pubmed/30746075
http://dx.doi.org/10.1039/c8sc03697g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335865/
https://www.ncbi.nlm.nih.gov/pubmed/30746075
http://dx.doi.org/10.1039/c8sc03697g

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