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Identifying and validating blood mRNA biomarkers for acute and chronic insufficient sleep in humans: a machine learning approach

Acute and chronic insufficient sleep are associated with adverse health outcomes and risk of accidents. There is therefore a need for biomarkers to monitor sleep debt status. None are currently available. We applied elastic net and ridge regression to transcriptome samples collected in 36 healthy yo...

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Detalles Bibliográficos
Autores principales: Laing, Emma E, Möller-Levet, Carla S, Dijk, Derk-Jan, Archer, Simon N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335875/
https://www.ncbi.nlm.nih.gov/pubmed/30247731
http://dx.doi.org/10.1093/sleep/zsy186