Photoactivatable platinum anticancer complex can generate tryptophan radicals

l-Tryptophan (Trp), melatonin (MLT) and the Trp-peptide pentagastrin quenched the formation of azidyl radicals generated on irradiation of the anticancer complex trans,trans,trans-[Pt(pyridine)(2)(N(3))(2)(OH)(2)] with visible light, giving rise to C3-centred indole radicals which were characterized...

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Detalles Bibliográficos
Autores principales: Vallotto, Claudio, Shaili, Evyenia, Shi, Huayun, Butler, Jennifer S., Wedge, Christopher J., Newton, Mark E., Sadler, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336088/
https://www.ncbi.nlm.nih.gov/pubmed/30468213
http://dx.doi.org/10.1039/c8cc06496b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336088/
https://www.ncbi.nlm.nih.gov/pubmed/30468213
http://dx.doi.org/10.1039/c8cc06496b

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