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Distinct Stress Response and Altered Striatal Transcriptome in Alpha-Synuclein Overexpressing Mice

Parkinson’s disease (PD) is a progressive neurodegenerative disorder with motor symptoms and a plethora of non-motor and neuropsychiatric features that accompany the disease from prodromal to advanced stages. While several genetic defects have been identified in familial forms of PD, the predominanc...

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Detalles Bibliográficos
Autores principales: Wassouf, Zinah, Hentrich, Thomas, Casadei, Nicolas, Jaumann, Mirko, Knipper, Marlies, Riess, Olaf, Schulze-Hentrich, Julia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336091/
https://www.ncbi.nlm.nih.gov/pubmed/30686992
http://dx.doi.org/10.3389/fnins.2018.01033