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Mouse DCUN1D1 (SCCRO) is required for spermatogenetic individualization

Squamous cell carcinoma–related oncogene (SCCRO, also known as DCUN1D1) is a component of the E3 for neddylation. As such, DCUN1D1 regulates the neddylation of cullin family members. Targeted inactivation of DCUN1D1 in mice results in male-specific infertility. Infertility in DCUN1D1(-/-) mice is se...

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Detalles Bibliográficos
Autores principales: Huang, Guochang, Kaufman, Andrew J., Ryan, Russell J. H., Romin, Yevgeniy, Huryn, Laryssa, Bains, Sarina, Manova-Todorova, Katia, Morris, Patricia L., Hunnicutt, Gary R., Adelman, Carrie A., Petrini, John H. J., Ramanathan, Y., Singh, Bhuvanesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336273/
https://www.ncbi.nlm.nih.gov/pubmed/30653527
http://dx.doi.org/10.1371/journal.pone.0209995