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Effects of skeletal unloading on the antibody repertoire of tetanus toxoid and/or CpG treated C57BL/6J mice

Spaceflight affects the immune system, but the effects on the antibody repertoire, responsible for humoral immunity, has not been well explored. In particular, the complex gene assembly and expression process; including mutations, might make this process vulnerable. Complementarity determining regio...

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Detalles Bibliográficos
Autores principales: Rettig, Trisha A., Bye, Bailey A., Nishiyama, Nina C., Hlavacek, Savannah, Ward, Claire, Pecaut, Michael J., Chapes, Stephen K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336310/
https://www.ncbi.nlm.nih.gov/pubmed/30653556
http://dx.doi.org/10.1371/journal.pone.0210284