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Narya, a RING finger domain-containing protein, is required for meiotic DNA double-strand break formation and crossover maturation in Drosophila melanogaster

Meiotic recombination, which is necessary to ensure that homologous chromosomes segregate properly, begins with the induction of meiotic DNA double-strand breaks (DSBs) and ends with the repair of a subset of those breaks into crossovers. Here we investigate the roles of two paralogous genes, CG1220...

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Detalles Bibliográficos
Autores principales: Lake, Cathleen M., Nielsen, Rachel J., Bonner, Amanda M., Eche, Salam, White-Brown, Sanese, McKim, Kim S., Hawley, R. Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336347/
https://www.ncbi.nlm.nih.gov/pubmed/30615609
http://dx.doi.org/10.1371/journal.pgen.1007886