A transient helix in the disordered region of dynein light intermediate chain links the motor to structurally diverse adaptors for cargo transport

All animal cells use the motor cytoplasmic dynein 1 (dynein) to transport diverse cargo toward microtubule minus ends and to organize and position microtubule arrays such as the mitotic spindle. Cargo-specific adaptors engage with dynein to recruit and activate the motor, but the molecular mechanism...

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Detalles Bibliográficos
Autores principales: Celestino, Ricardo, Henen, Morkos A., Gama, José B., Carvalho, Cátia, McCabe, Maxwell, Barbosa, Daniel J., Born, Alexandra, Nichols, Parker J., Carvalho, Ana X., Gassmann, Reto, Vögeli, Beat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336354/
https://www.ncbi.nlm.nih.gov/pubmed/30615611
http://dx.doi.org/10.1371/journal.pbio.3000100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336354/
https://www.ncbi.nlm.nih.gov/pubmed/30615611
http://dx.doi.org/10.1371/journal.pbio.3000100

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