Cargando…

The elemental mechanism of transcriptional pausing

Transcriptional pausing underlies regulation of cellular RNA biogenesis. A consensus pause sequence that acts on RNA polymerases (RNAPs) from bacteria to mammals halts RNAP in an elemental paused state from which longer-lived pauses can arise. Although the structural foundations of pauses prolonged...

Descripción completa

Detalles Bibliográficos
Autores principales: Saba, Jason, Chua, Xien Yu, Mishanina, Tatiana V, Nayak, Dhananjaya, Windgassen, Tricia A, Mooney, Rachel Anne, Landick, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336406/
https://www.ncbi.nlm.nih.gov/pubmed/30618376
http://dx.doi.org/10.7554/eLife.40981