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CO(2) Signaling through the Ptc2-Ssn3 Axis Governs Sustained Hyphal Development of Candida albicans by Reducing Ume6 Phosphorylation and Degradation

Candida albicans is the most common cause of invasive fungal infections in humans. Its ability to sense and adapt to changing carbon dioxide levels is crucial for its pathogenesis. Carbon dioxide promotes hyphal development. The hypha-specific transcription factor Ume6 is rapidly degraded in air, bu...

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Detalles Bibliográficos
Autores principales: Lu, Yang, Su, Chang, Ray, Shatarupa, Yuan, Yuncong, Liu, Haoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336421/
https://www.ncbi.nlm.nih.gov/pubmed/30647154
http://dx.doi.org/10.1128/mBio.02320-18