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Micro-scaled topographies direct differentiation of human epidermal stem cells

Human epidermal stem cells initiate terminal differentiation when spreading is restricted on ECM-coated micropatterned islands, soft hydrogels or hydrogel-nanoparticle composites with high nanoparticle spacing. The effect of substrate topography, however, is incompletely understood. To explore this,...

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Detalles Bibliográficos
Autores principales: Zijl, Sebastiaan, Vasilevich, Aliaksei S., Viswanathan, Priyalakshmi, Helling, Ayelen Luna, Beijer, Nick R.M., Walko, Gernot, Chiappini, Ciro, de Boer, Jan, Watt, Fiona M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336537/
https://www.ncbi.nlm.nih.gov/pubmed/30528608
http://dx.doi.org/10.1016/j.actbio.2018.12.003