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Interpretation of the mechanism of action of antituberculosis drug bedaquiline based on a novel two‐ion theory of energy coupling in ATP synthesis
Tuberculosis (TB) claims the lives of 1.3 million people each year, more than any other bacterial infection. Hence great interest was generated in health communities upon the recent introduction of the new diarylquinoline anti‐TB drug, bedaquiline. Bedaquiline acts by binding to the c‐subunit in the...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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John Wiley & Sons, Inc.
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336660/ https://www.ncbi.nlm.nih.gov/pubmed/30680327 http://dx.doi.org/10.1002/btm2.10106 |