Rescuing mesenchymal stem cell regenerative properties on hydrogel substrates post serial expansion

The use of human mesenchymal stem/stromal cells (hMSCs) in most clinical trials requires millions of cells/kg, necessitating ex vivo expansion typically on stiff substrates (tissue culture polystyrene [TCPS]), which induces osteogenesis and replicative senescence. Here, we quantified how serial expa...

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Detalles Bibliográficos
Autores principales: Rao, Varsha V., Vu, Michael K., Ma, Hao, Killaars, Anouk R., Anseth, Kristi S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2018
Materias:
Research Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336661/
https://www.ncbi.nlm.nih.gov/pubmed/30680318
http://dx.doi.org/10.1002/btm2.10104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336661/
https://www.ncbi.nlm.nih.gov/pubmed/30680318
http://dx.doi.org/10.1002/btm2.10104

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