Device design methodology and formulation of a protein therapeutic for sustained release intraocular delivery

Despite years of effort, sustained delivery of protein therapeutics remains an unmet need due to three primary challenges – dose, duration, and stability. The work presented here provides a design methodology for polycaprolactone reservoir‐based thin film devices suitable for long‐acting protein del...

Descripción completa

Detalles Bibliográficos
Autores principales: Schlesinger, Erica B., Bernards, Daniel A., Chen, Hunter H., Feindt, James, Cao, Jingtai, Dix, Daniel, Romano, Carmelo, Bhisitkul, Robert B., Desai, Tejal A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2018
Materias:
Research Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336666/
https://www.ncbi.nlm.nih.gov/pubmed/30680326
http://dx.doi.org/10.1002/btm2.10121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336666/
https://www.ncbi.nlm.nih.gov/pubmed/30680326
http://dx.doi.org/10.1002/btm2.10121

Ejemplares similares