Cargando…

Device design methodology and formulation of a protein therapeutic for sustained release intraocular delivery

Despite years of effort, sustained delivery of protein therapeutics remains an unmet need due to three primary challenges – dose, duration, and stability. The work presented here provides a design methodology for polycaprolactone reservoir‐based thin film devices suitable for long‐acting protein del...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schlesinger, Erica B., Bernards, Daniel A., Chen, Hunter H., Feindt, James, Cao, Jingtai, Dix, Daniel, Romano, Carmelo, Bhisitkul, Robert B., Desai, Tejal A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2018
Materias:	Research Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336666/ https://www.ncbi.nlm.nih.gov/pubmed/30680326 http://dx.doi.org/10.1002/btm2.10121

Ejemplares similares

Formulation and Optimization of Sustained Release Stavudine Microspheres Using Response Surface Methodology
por: Dey, Sanjay, et al.
Publicado: (2011)

Sustained Release Intraocular Drug Delivery Devices for Treatment of Uveitis
por: Haghjou, Nahid, et al.
Publicado: (2011)

Glass intraocular foreign body removal with a nitinol stone basket
por: Francis, Andrew W., et al.
Publicado: (2019)

Formulation and Optimization of Sustained Release Tablets of Venlafaxine Resinates Using Response Surface Methodology
por: Madgulkar, Ashwini R., et al.
Publicado: (2009)

Use of Response Surface Methodology in the Formulation and Optimization of Bisoprolol Fumarate Matrix Tablets for Sustained Drug Release
por: Malakar, Jadupati, et al.
Publicado: (2012)

Biocompatibility and Pharmacokinetic Analysis of an Intracameral Polycaprolactone Drug Delivery Implant for Glaucoma
por: Kim, Jean, et al.
Publicado: (2016)

Formulation, evaluation and optimization of sustained release matrix tablets of captopril
por: Pandya, V. Pandya, et al.
Publicado: (2012)

Cyclodextrin-containing hydrogels as an intraocular lens for sustained drug release
por: Li, Xiao, et al.
Publicado: (2017)

Formulation, optimization and evaluation of sustained release microsphere of ketoprofen
por: Prajapati, Chirag V., et al.
Publicado: (2012)

Eprinomectin from a sustained release formulation adversely affected dung breeding insects
por: Nieman, Christine C., et al.
Publicado: (2018)

Feasibility study of sustained-release travoprost punctum plug for intraocular pressure reduction in an Asian population
por: Perera, Shamira A, et al.
Publicado: (2016)

Intraocular Pressure Effects and Mechanism of Action of Topical Versus Sustained-Release Bimatoprost
por: Lee, Susan S., et al.
Publicado: (2019)

A comparative study between a transscleral sustained-release device and eyedrops on intraocular distribution of carteolol hydrochloride
por: Hashikawa, Yoshiko, et al.
Publicado: (2023)

A clinical study to compare the efficacy and safety of pregabalin sustained release formulation with pregabalin immediate release formulation in patients of diabetic peripheral neuropathic pain
por: Srivastava, A., et al.
Publicado: (2012)

Sustained-release nanoART formulation for the treatment of neuroAIDS
por: Jayant, Rahul Dev, et al.
Publicado: (2015)

Formulation of a Hybrid Nanofertilizer for Slow and Sustainable Release of Micronutrients
por: Tarafder, Chaitaly, et al.
Publicado: (2020)

In Vitro and In Vivo Evaluation of Inhalable Ciprofloxacin Sustained Release Formulations
por: Shi, Changzhi, et al.
Publicado: (2023)

Formulation Design, Optimization and Pharmacodynamic Evaluation of Sustained Release Mucoadhesive Microcapsules of Venlafaxine HCl
por: Swain, S., et al.
Publicado: (2014)

Drug-eluting intraocular lens with sustained bromfenac release for conquering posterior capsular opacification
por: Zhang, Xiaobo, et al.
Publicado: (2021)

Formulation and characterization of sustained release dosage form of moisture sensitive drug
por: Patel, Priya, et al.
Publicado: (2015)

Pharmacokinetic-Pharmacodynamic Model of Newly Developed Dexibuprofen Sustained Release Formulations
por: Muralidharan, Selvadurai
Publicado: (2012)

Development of Sustained-Release Ophthalmic Formulation Based on Tranilast Solid Nanoparticles
por: Minami, Misa, et al.
Publicado: (2020)

Formulation and Evaluation of Xanthan Gum Microspheres for the Sustained Release of Metformin Hydrochloride
por: Yahoum, Madiha Melha, et al.
Publicado: (2023)

Formulation of Sustained Release Hydrophilic Matrix Tablets of Tolcapone with the Application of Sedem Diagram: Influence of Tolcapone’s Particle Size on Sustained Release
por: Nardi-Ricart, Anna, et al.
Publicado: (2020)

Preparation and in vitro release kinetics of ivermectin sustained-release bolus optimized by response surface methodology
por: Ruan, Xiangchun, et al.
Publicado: (2018)

Selection of 12‐Hour Sustained‐Release Acetaminophen (Paracetamol) Formulation Through Comparison of Pharmacokinetic Profiles of 4 Sustained‐Release Prototype Formulations and Standard Acetaminophen Formulation: An Open‐Label, Randomized, Proof‐of‐Principle Pharmacokinetic Study
por: Yue, Yong, et al.
Publicado: (2017)

Nanotechnology-based formulations to amplify intraocular bioavailability
por: Kagkelaris, Konstantinos, et al.
Publicado: (2022)

Dose–Response of Intracameral Bimatoprost Sustained-Release Implant and Topical Bimatoprost in Lowering Intraocular Pressure
por: Lee, Susan S., et al.
Publicado: (2019)

In Vivo Sustained Release of the Retrograde Transport Inhibitor Retro-2.1 Formulated in a Thermosensitive Hydrogel
por: Vinck, Robin, et al.
Publicado: (2022)

Optimization of Salbutamol Sulfate Dissolution from Sustained Release Matrix Formulations Using an Artificial Neural Network
por: Chaibva, Faith, et al.
Publicado: (2010)

Preparation, Characterization and in vivo Evaluation of Parenteral Sustained Release Microsphere Formulation of Zopiclone
por: Swapna, N, et al.
Publicado: (2010)

Formulation and evaluation of sustained release enteric-coated pellets of budesonide for intestinal delivery
por: Raval, Mihir K, et al.
Publicado: (2013)

Biochronomer™ technology and the development of APF530, a sustained release formulation of granisetron
por: Ottoboni, Thomas, et al.
Publicado: (2014)

Chitosan-Montmorillonite Polymer Composites: Formulation and Evaluation of Sustained Release Tablets of Aceclofenac
por: Thakur, Garima, et al.
Publicado: (2015)

Investigation of the potential application of sodium bentonite as an excipient in formulation of sustained release tablets
por: Alkrad, Jamal Alyoussef, et al.
Publicado: (2017)

Carbamazepine Gel Formulation as a Sustained Release Epilepsy Medication for Pediatric Use
por: Mawazi, Saeid Mezail, et al.
Publicado: (2019)

An in vivo pharmacokinetic study of metformin microparticles as an oral sustained release formulation in rabbits
por: Bouriche, Sihem, et al.
Publicado: (2021)

Design and Optimization of Diclofenac Sodium Controlled Release Solid Dispersions by Response Surface Methodology
por: Shivakumar, H. N., et al.
Publicado: (2008)

Sustained release of brimonidine from polydimethylsiloxane-coating silicone rubber implant to reduce intraocular pressure in glaucoma
por: Huang, Chang, et al.
Publicado: (2023)

Design, Development and Optimization of S (-) Atenolol Floating Sustained Release Matrix Tablets Using Surface Response Methodology
por: Gunjal, P. T., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_esh5sanh7avtpr7icgrh9oaihs