The role of PIP5K1α/pAKT and targeted inhibition of growth of subtypes of breast cancer using PIP5K1α inhibitor

Despite recent improvement in adjuvant therapies, triple-negative, and ER(+) subtypes of breast cancer (BC) with metastatic potentials remain the leading cause of BC-related deaths. We investigated the role of phosphatidylinositol-4-phosphate 5-kinase alpha (PIP5Kα), a key upstream factor of PI3K/AK...

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Detalles Bibliográficos
Autores principales: Sarwar, Martuza, Syed Khaja, Azharuddin Sajid, Aleskandarany, Mohammed, Karlsson, Richard, Althobiti, Maryam, Ødum, Niels, Mongan, Nigel P., Dizeyi, Nisthman, Johnson, Heather, Green, Andrew R., Ellis, Ian O., Rakha, Emad A., Persson, Jenny L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336681/
https://www.ncbi.nlm.nih.gov/pubmed/30104711
http://dx.doi.org/10.1038/s41388-018-0438-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336681/
https://www.ncbi.nlm.nih.gov/pubmed/30104711
http://dx.doi.org/10.1038/s41388-018-0438-2

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