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The role of PIP5K1α/pAKT and targeted inhibition of growth of subtypes of breast cancer using PIP5K1α inhibitor
Despite recent improvement in adjuvant therapies, triple-negative, and ER(+) subtypes of breast cancer (BC) with metastatic potentials remain the leading cause of BC-related deaths. We investigated the role of phosphatidylinositol-4-phosphate 5-kinase alpha (PIP5Kα), a key upstream factor of PI3K/AK...
Autores principales: | Sarwar, Martuza, Syed Khaja, Azharuddin Sajid, Aleskandarany, Mohammed, Karlsson, Richard, Althobiti, Maryam, Ødum, Niels, Mongan, Nigel P., Dizeyi, Nisthman, Johnson, Heather, Green, Andrew R., Ellis, Ian O., Rakha, Emad A., Persson, Jenny L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336681/ https://www.ncbi.nlm.nih.gov/pubmed/30104711 http://dx.doi.org/10.1038/s41388-018-0438-2 |
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