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A novel cross-talk between CXCR4 and PI4KIIIα in prostate cancer cells.

Chemokine signaling regulates cell migration and tumor metastasis. CXCL12, a member of the chemokine family, and its receptor, CXCR4, a G protein coupled receptor (GPCR), are key mediators of prostate-cancer (PC) bone metastasis. In PC cells androgens activate CXCR4 gene expression and receptor sign...

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Detalles Bibliográficos
Autores principales: Sbrissa, Diego, Semaan, Louie, Govindarajan, Barani, Li, Yanfeng, Caruthers, Nicholas J., Stemmer, Paul M., Cher, Michael L., Sethi, Seema, Vaishampayan, Ulka, Shisheva, Assia, Chinni, Sreenivasa R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336684/
https://www.ncbi.nlm.nih.gov/pubmed/30111818
http://dx.doi.org/10.1038/s41388-018-0448-0