Cargando…

A novel cross-talk between CXCR4 and PI4KIIIα in prostate cancer cells.

Chemokine signaling regulates cell migration and tumor metastasis. CXCL12, a member of the chemokine family, and its receptor, CXCR4, a G protein coupled receptor (GPCR), are key mediators of prostate-cancer (PC) bone metastasis. In PC cells androgens activate CXCR4 gene expression and receptor sign...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sbrissa, Diego, Semaan, Louie, Govindarajan, Barani, Li, Yanfeng, Caruthers, Nicholas J., Stemmer, Paul M., Cher, Michael L., Sethi, Seema, Vaishampayan, Ulka, Shisheva, Assia, Chinni, Sreenivasa R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336684/ https://www.ncbi.nlm.nih.gov/pubmed/30111818 http://dx.doi.org/10.1038/s41388-018-0448-0

Ejemplares similares

Adaptor proteins mediate CXCR4 and PI4KA crosstalk in prostate cancer cells and the significance of PI4KA in bone tumor growth
por: Govindarajan, Barani, et al.
Publicado: (2023)

Adaptor proteins mediate CXCR4 and PI4KA crosstalk in prostate cancer cells and the significance of PI4KA in bone tumor growth
por: Govindarajan, Barani, et al.
Publicado: (2023)

Pharmacological targeting of CXCL12/CXCR4 signaling in prostate cancer bone metastasis
por: Conley-LaComb, M. Katie, et al.
Publicado: (2016)

TMPRSS2-ERG fusions confer efficacy of enzalutamide in an in vivo bone tumor growth model
por: Semaan, Louie, et al.
Publicado: (2019)

Plasticity of PI4KIIIα interactions at the plasma membrane
por: Chung, Jeeyun, et al.
Publicado: (2015)

Apilimod, a candidate anticancer therapeutic, arrests not only PtdIns(3,5)P(2) but also PtdIns5P synthesis by PIKfyve and induces bafilomycin A1-reversible aberrant endomembrane dilation
por: Sbrissa, Diego, et al.
Publicado: (2018)

Targeting CXCR4 with CTCE-9908 inhibits prostate tumor metastasis
por: Wong, Donald, et al.
Publicado: (2014)

Covalent targeting of non-cysteine residues in PI4KIIIβ
por: Cosgrove, Brett, et al.
Publicado: (2023)

Clinical Efficacy of Enzalutamide vs Bicalutamide Combined With Androgen Deprivation Therapy in Men With Metastatic Hormone-Sensitive Prostate Cancer: A Randomized Clinical Trial
por: Vaishampayan, Ulka N., et al.
Publicado: (2021)

PTEN loss mediated Akt activation promotes prostate tumor growth and metastasis via CXCL12/CXCR4 signaling
por: Conley-LaComb, M Katie, et al.
Publicado: (2013)

Unexpected severe consequences of Pikfyve deletion by aP2‐ or Aq‐promoter‐driven Cre expression for glucose homeostasis and mammary gland development
por: Ikonomov, Ognian C., et al.
Publicado: (2016)

Differential effects of the phosphatidylinositol 4-kinases, PI4KIIα and PI4KIIIβ, on Akt activation and apoptosis
por: Chu, K M E, et al.
Publicado: (2010)

Vibrator and PI4KIIIα govern neuroblast polarity by anchoring non-muscle myosin II
por: Koe, Chwee Tat, et al.
Publicado: (2018)

Fragment-based virtual screening discovers potential new Plasmodium PI4KIIIβ ligands
por: Ibezim, Akachukwu, et al.
Publicado: (2022)

PtdIns4P synthesis by PI4KIIIα at the plasma membrane and its impact on plasma membrane identity
por: Nakatsu, Fubito, et al.
Publicado: (2012)

Hepatitis C Virus Subverts Human Choline Kinase-α To Bridge Phosphatidylinositol-4-Kinase IIIα (PI4KIIIα) and NS5A and Upregulates PI4KIIIα Activation, Thereby Promoting the Translocation of the Ternary Complex to the Endoplasmic Reticulum for Viral Replication
por: Wong, Mun-Teng, et al.
Publicado: (2017)

Novel phosphatidylinositol 4-kinases III beta (PI4KIIIβ) inhibitors discovered by virtual screening using free energy models
por: Colodette, Natalie M., et al.
Publicado: (2020)

CXCR4 and CXCR7 Signaling Pathways: A Focus on the Cross-Talk Between Cancer Cells and Tumor Microenvironment
por: Santagata, Sara, et al.
Publicado: (2021)

The Year in Review for Renal Cancer
por: Vaishampayan, Ulka
Publicado: (2020)

The power of meta-analysis in therapeutic decision making for advanced kidney cancer
por: Vaishampayan, Ulka
Publicado: (2019)

Bithiazole Inhibitors of Phosphatidylinositol 4‐Kinase (PI4KIIIβ) as Broad‐Spectrum Antivirals Blocking the Replication of SARS‐CoV‐2, Zika Virus, and Human Rhinoviruses
por: Grazia Martina, Maria, et al.
Publicado: (2021)

Functional Cross Talk between CXCR4 and PDGFR on Glioblastoma Cells Is Essential for Migration
por: Sciaccaluga, Miriam, et al.
Publicado: (2013)

Using hydrogen deuterium exchange mass spectrometry to engineer optimized constructs for crystallization of protein complexes: Case study of PI4KIIIβ with Rab11
por: Fowler, Melissa L., et al.
Publicado: (2016)

Development of cabozantinib for the treatment of prostate cancer
por: Vaishampayan, Ulka N
Publicado: (2014)

Novel lipid mediators contributing to androgen receptor therapy resistance in prostate cancer
por: Chinni, Sreenivasa R.
Publicado: (2021)

Predictors of Cytoreductive Nephrectomy for Metastatic Kidney Cancer in SEER and Metropolitan Detroit Databases
por: Vaishampayan, Ulka, et al.
Publicado: (2019)

Targeting of CXCR4 by the Naturally Occurring CXCR4 Antagonist EPI-X4 in Waldenström’s Macroglobulinemia
por: Kaiser, Lisa Marie, et al.
Publicado: (2021)

Flash Talk 4
por: Garcia Montero, Oscar
Publicado: (2020)

Immunotherapy and Immune Evasion in Prostate Cancer
por: Thakur, Archana, et al.
Publicado: (2013)

Calcineurin/CXCR4 in T-ALL
por: Passaro, Diana, et al.
Publicado: (2015)

Opposing roles of CXCR4 and CXCR7 in breast cancer metastasis
por: Hernandez, Lorena, et al.
Publicado: (2011)

Correlation of CXCR4/CXCR7 signaling pathway with pre-eclampsia
por: Zheng, Zhi, et al.
Publicado: (2018)

Specific Receptors for the Chemokines CXCR2 and CXCR4 in Pancreatic Cancer
por: Litman-Zawadzka, Ala, et al.
Publicado: (2020)

Inhibition of CXCR4 and CXCR7 Is Protective in Acute Peritoneal Inflammation
por: Ngamsri, Kristian-Christos, et al.
Publicado: (2020)

Role of platelet-derived microparticles in transfer of the chemokine receptor CXCR4 to CXCR4-negative cells
por: Manoochehrabadi, Tahereh, et al.
Publicado: (2019)

Class Room Talks, No. 4
Publicado: (1888)

Agonists for the Chemokine Receptor CXCR4
por: Lefrançois, Marilou, et al.
Publicado: (2011)

Small Molecule Inhibitors of CXCR4
por: Debnath, Bikash, et al.
Publicado: (2013)

AMD3100/CXCR4 Inhibitor
por: De Clercq, Erik
Publicado: (2015)

CXCR4 involvement in neurodegenerative diseases
por: Bonham, Luke W., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_rvm0l687hgme0kfe6t6cameo07