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Representing dynamic biological networks with multi-scale probabilistic models

Dynamic models analyzing gene regulation and metabolism face challenges when adapted to modeling signal transduction networks. During signal transduction, molecular reactions and mechanisms occur in different spatial and temporal frames and involve feedbacks. This impedes the straight-forward use of...

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Detalles Bibliográficos
Autores principales: Groß, Alexander, Kracher, Barbara, Kraus, Johann M., Kühlwein, Silke D., Pfister, Astrid S., Wiese, Sebastian, Luckert, Katrin, Pötz, Oliver, Joos, Thomas, Van Daele, Dries, De Raedt, Luc, Kühl, Michael, Kestler, Hans A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336720/
https://www.ncbi.nlm.nih.gov/pubmed/30675519
http://dx.doi.org/10.1038/s42003-018-0268-3