Cargando…
Method of establishing breast cancer brain metastases affects brain uptake and efficacy of targeted, therapeutic nanoparticles
HER2‐targeted therapies effectively control systemic disease, but their efficacy against brain metastases is hindered by their low penetration of the blood‐brain and blood‐tumor barriers (BBB and BTB). We investigate brain uptake and antitumor efficacy of transferrin receptor (TfR)‐targeted, therape...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley & Sons, Inc.
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336738/ https://www.ncbi.nlm.nih.gov/pubmed/30680316 http://dx.doi.org/10.1002/btm2.10108 |