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Measurement of the total angiotensinogen and its reduced and oxidised forms in human plasma using targeted LC-MS/MS
Angiotensinogen (AGT) is a critical protein in the renin-angiotensin-aldosterone system and may have an important role in the pathogenesis of pre-eclampsia. The disulphide linkage between cysteines 18 and 138 has a key role in the redox switch of AGT which modulates the release of angiotensin I with...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336742/ https://www.ncbi.nlm.nih.gov/pubmed/30465161 http://dx.doi.org/10.1007/s00216-018-1455-2 |