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Measurement of the total angiotensinogen and its reduced and oxidised forms in human plasma using targeted LC-MS/MS

Angiotensinogen (AGT) is a critical protein in the renin-angiotensin-aldosterone system and may have an important role in the pathogenesis of pre-eclampsia. The disulphide linkage between cysteines 18 and 138 has a key role in the redox switch of AGT which modulates the release of angiotensin I with...

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Detalles Bibliográficos
Autores principales: Dahabiyeh, Lina A., Tooth, David, Carrell, Robin W., Read, Randy J., Yan, Yahui, Pipkin, Fiona Broughton, Barrett, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336742/
https://www.ncbi.nlm.nih.gov/pubmed/30465161
http://dx.doi.org/10.1007/s00216-018-1455-2