Tip60- and sirtuin 2-regulated MARCKS acetylation and phosphorylation are required for diabetic embryopathy

Failure of neural tube closure results in severe birth defects and can be induced by high glucose levels resulting from maternal diabetes. MARCKS is required for neural tube closure, but the regulation and of its biological activity and function have remained elusive. Here, we show that high materna...

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Detalles Bibliográficos
Autores principales: Yang, Penghua, Xu, Cheng, Reece, E. Albert, Chen, Xi, Zhong, Jianxiang, Zhan, Min, Stumpo, Deborah J., Blackshear, Perry J., Yang, Peixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336777/
https://www.ncbi.nlm.nih.gov/pubmed/30655546
http://dx.doi.org/10.1038/s41467-018-08268-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336777/
https://www.ncbi.nlm.nih.gov/pubmed/30655546
http://dx.doi.org/10.1038/s41467-018-08268-6

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