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Rifaximin alters gut microbiota profile, but does not affect systemic inflammation - a randomized controlled trial in common variable immunodeficiency

Common variable immunodeficiency (CVID) patients have reduced gut microbial diversity compared to healthy controls. The reduced diversity is associated with gut leakage, increased systemic inflammation and ten “key” bacteria that capture the gut dysbiosis (dysbiosis index) in CVID. Rifaximin is a br...

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Detalles Bibliográficos
Autores principales: Jørgensen, S. F., Macpherson, M. E., Bjørnetrø, T., Holm, K., Kummen, M., Rashidi, A., Michelsen, A. E., Lekva, T., Halvorsen, B., Trøseid, M., Mollnes, T. E., Berge, R. K., Yndestad, A., Ueland, T., Karlsen, T. H., Aukrust, P., Hov, J. R., Fevang, B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336782/
https://www.ncbi.nlm.nih.gov/pubmed/30655568
http://dx.doi.org/10.1038/s41598-018-35367-7