An automated Bayesian pipeline for rapid analysis of single-molecule binding data

Single-molecule binding assays enable the study of how molecular machines assemble and function. Current algorithms can identify and locate individual molecules, but require tedious manual validation of each spot. Moreover, no solution for high-throughput analysis of single-molecule binding data exi...

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Detalles Bibliográficos
Autores principales: Smith, Carlas S., Jouravleva, Karina, Huisman, Maximiliaan, Jolly, Samson M., Zamore, Phillip D., Grunwald, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336789/
https://www.ncbi.nlm.nih.gov/pubmed/30655518
http://dx.doi.org/10.1038/s41467-018-08045-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336789/
https://www.ncbi.nlm.nih.gov/pubmed/30655518
http://dx.doi.org/10.1038/s41467-018-08045-5

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