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A 14-day repeat dose oral gavage range-finding study of a first-in-class CDI investigational antibiotic, in rats

Drug resistant bacteria are winning the fight over antibiotics with some bacteria not responding to any antibiotics, threatening modern medicine as we know it. The development of new, effective and safe antibiotics is critical for addressing this issue. Ramizol, a first-in-class styrylbenzene based...

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Detalles Bibliográficos
Autores principales: Sibley, Katherine, Chen, Jayson, Koetzner, Lee, Mendes, Odete, Kimzey, Amy, Lansita, Janice, Boulos, Ramiz A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336794/
https://www.ncbi.nlm.nih.gov/pubmed/30655592
http://dx.doi.org/10.1038/s41598-018-36690-9