TCR microclusters form spatially segregated domains and sequentially assemble in calcium-dependent kinetic steps

Engagement of the T cell receptor (TCR) by stimulatory ligand results in the rapid formation of microclusters at sites of T cell activation. Whereas microclusters have been studied extensively using confocal microscopy, the spatial and kinetic relationships of their signaling components have not bee...

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Detalles Bibliográficos
Autores principales: Yi, Jason, Balagopalan, Lakshmi, Nguyen, Tiffany, McIntire, Katherine M., Samelson, Lawrence E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336795/
https://www.ncbi.nlm.nih.gov/pubmed/30655520
http://dx.doi.org/10.1038/s41467-018-08064-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336795/
https://www.ncbi.nlm.nih.gov/pubmed/30655520
http://dx.doi.org/10.1038/s41467-018-08064-2

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