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TCR microclusters form spatially segregated domains and sequentially assemble in calcium-dependent kinetic steps
Engagement of the T cell receptor (TCR) by stimulatory ligand results in the rapid formation of microclusters at sites of T cell activation. Whereas microclusters have been studied extensively using confocal microscopy, the spatial and kinetic relationships of their signaling components have not bee...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336795/ https://www.ncbi.nlm.nih.gov/pubmed/30655520 http://dx.doi.org/10.1038/s41467-018-08064-2 |