CBX6 is negatively regulated by EZH2 and plays a potential tumor suppressor role in breast cancer

Chromobox 6 (CBX6) is a subunit of Polycomb Repressive Complex 1 (PRC1) that mediates epigenetic gene repression and acts as an oncogene or tumor suppressor in a cancer type-dependent manner. The specific function of CBX6 in breast cancer is currently undefined. In this study, a comprehensive analys...

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Detalles Bibliográficos
Autores principales: Deng, Houliang, Guan, Xiaowen, Gong, Longcai, Zeng, Jianming, Zhang, Hongjie, Chen, Mike Y., Li, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336801/
https://www.ncbi.nlm.nih.gov/pubmed/30655550
http://dx.doi.org/10.1038/s41598-018-36560-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336801/
https://www.ncbi.nlm.nih.gov/pubmed/30655550
http://dx.doi.org/10.1038/s41598-018-36560-4

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