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Identification of selective inhibitors of Helicobacter pylori IMPDH as a targeted therapy for the infection

Helicobacter pylori (H. pylori), the major cause of several gastric disorders has been recognied as a type I carcinogen. By virtue of resistance developed by H. pylori strains, currently used antibiotic based treatments rather demonstrate high failure rates. Hence, there is an emerging need for iden...

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Detalles Bibliográficos
Autores principales: Juvale, Kapil, Purushothaman, Gayathri, Singh, Vijay, Shaik, Althaf, Ravi, Srimadhavi, Thiruvenkatam, Vijay, Kirubakaran, Sivapriya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336804/
https://www.ncbi.nlm.nih.gov/pubmed/30655593
http://dx.doi.org/10.1038/s41598-018-37490-x