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The impact of cigarette smoke exposure, COPD, or asthma status on ABC transporter gene expression in human airway epithelial cells

ABC transporters are conserved in prokaryotes and eukaryotes, with humans expressing 48 transporters divided into 7 classes (ABCA, ABCB, ABCC, ABCD, ABDE, ABCF, and ABCG). Throughout the human body, ABC transporters regulate cAMP levels, chloride secretion, lipid transport, and anti-oxidant response...

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Detalles Bibliográficos
Autores principales: Aguiar, Jennifer A., Tamminga, Andrea, Lobb, Briallen, Huff, Ryan D., Nguyen, Jenny P., Kim, Yechan, Dvorkin-Gheva, Anna, Stampfli, Martin R., Doxey, Andrew C., Hirota, Jeremy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336805/
https://www.ncbi.nlm.nih.gov/pubmed/30655622
http://dx.doi.org/10.1038/s41598-018-36248-9