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The impact of cigarette smoke exposure, COPD, or asthma status on ABC transporter gene expression in human airway epithelial cells
ABC transporters are conserved in prokaryotes and eukaryotes, with humans expressing 48 transporters divided into 7 classes (ABCA, ABCB, ABCC, ABCD, ABDE, ABCF, and ABCG). Throughout the human body, ABC transporters regulate cAMP levels, chloride secretion, lipid transport, and anti-oxidant response...
Autores principales: | Aguiar, Jennifer A., Tamminga, Andrea, Lobb, Briallen, Huff, Ryan D., Nguyen, Jenny P., Kim, Yechan, Dvorkin-Gheva, Anna, Stampfli, Martin R., Doxey, Andrew C., Hirota, Jeremy A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336805/ https://www.ncbi.nlm.nih.gov/pubmed/30655622 http://dx.doi.org/10.1038/s41598-018-36248-9 |
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