Overexpression of Trypanosoma cruzi High Mobility Group B protein (TcHMGB) alters the nuclear structure, impairs cytokinesis and reduces the parasite infectivity

Kinetoplastid parasites, included Trypanosoma cruzi, the causal agent of Chagas disease, present a unique genome organization and gene expression. Although they control gene expression mainly post-transcriptionally, chromatin accessibility plays a fundamental role in transcription initiation control...

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Detalles Bibliográficos
Autores principales: Tavernelli, Luis Emilio, Motta, Maria Cristina M., Gonçalves, Camila Silva, da Silva, Marcelo Santos, Elias, Maria Carolina, Alonso, Victoria Lucia, Serra, Esteban, Cribb, Pamela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336821/
https://www.ncbi.nlm.nih.gov/pubmed/30655631
http://dx.doi.org/10.1038/s41598-018-36718-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336821/
https://www.ncbi.nlm.nih.gov/pubmed/30655631
http://dx.doi.org/10.1038/s41598-018-36718-0

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